Body composition analysis by NMR
The minispec LF Series is a Whole Body Composition Analyzer based on TD-NMR that provides a precise method for measurement of lean tissue, fat, and fluid in living mice and rats. By carefully handling the animal without using any anaesthetics, a new standard for longitudinal studies has been established.
The minispec LF Series has quickly gained market acceptance as a powerful, non-destructive, and non-invasive mice analysis tool for characterising, screening and mouse phenotyping in research laboratories. It has become the industrial standard for fat and lean measurement in live mice with installations in major pharmaceutical companies, diabetes and obesity research institutes and universities.
Nuclear Magnetic Resonance (NMR) methods are among the most useful non-destructive techniques of material analysis. Non-invasive examination of the body by means of NMR is extensive and has many useful applications, particularly with Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS). TD-NMR uses similar NMR technology, providing analysis of fat tissue, lean tissue and free fluid by the same physical selection rules that give rise to contrast in MRI. Tissue contrast is high between fat and muscle based on relative relaxation times.
